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Astellas Pharma Research Associate II, R&D Cell Therapy in Westborough, Massachusetts

The Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.

Developing innovative therapies is one of the most challenging, most essential and personally rewarding fields in science. This is the most exciting time to be a part of Astellas, a company with a uniquely collaborative and patient-focused culture. There's something special about working at Astellas. It's reflected in our focus on the people we serve, the way we treat each other and the results we achieve together as a company.

AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell-based therapy research programs. AIRM is headquartered in Marlborough, Massachusetts.

Astellas is announcing a Research Associate II, R&D Cell Therapy opportunity at their Astellas Institute of Regenerative Medicine (AIRM) site in Westborough, MA.

Purpose:

We are seeking a highly motivated and energetic Research Associate to join the Research and Development team. This candidate will assist and troubleshoot exploratory research projects by performing mammalian cell culture, cell and molecular biology, and maintain accurate records for potential clinical applications. This position is highly collaborative, with on-the-job training to support the driven candidate's development and success.

Essential Job Responsibilities:

  • Perform mammalian cell culture (stem cells or epithelial/endothelial cells) using aseptic techniques

  • Ability to follow established protocols and execute in vitro assays, including transwell culture systems, cell viability assays, flow cytometry, and cell imaging

  • Maintains detailed, accurate record-keeping, contributing to SOPs and technical reports

  • Ensures availability of experimental materials

  • Familiarity with in vivo models

  • Summarizes results and communicates independently to team members

Qualifications:

Required

  • BS with 3+ years, or MS with 0-2 years of relevant laboratory experience.

  • Solid cell culture experience using aseptic technique, e.g. seeding, passaging, maintaining cells in culture, and banking cells

  • Familiarity with cell-based functional assays

  • Comfortable with in vivo models

  • Scientific curiosity coupled with desire to learn new skills

  • Superb written and oral communication skills to foster collaboration

  • Proficiency in Excel or GraphPad Prism, Word, PowerPoint

  • Ability to work flexible schedule, including weekends

  • Must have lawful immigration status to work legally for US firms

Preferred

  • Experience with human adult stem cell culture, mesenchymal stem cells and endothelial/epithelial cells.

  • Experience with in vitro barrier models, such as cell stress, cell polarization, extravasation, transepithelial/endothelial electrical resistance

  • Expertise on cell lineage characterization immunoassays using flow cytometry, immunofluorescence, cell isolation using FACS sorting and magnetic beads isolation, etc.

  • Hands-on in vivo model experience (handling or in-life data capture)

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Category Research and Development

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans

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