Astellas Pharmaceutical Jobs

Job Information

Astellas Pharma Research Associate II, Process Science & Technology in Westborough, Massachusetts

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at .

Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma Inc and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.

AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell-based therapy research programs. AIRM is headquartered in Massachusetts.

Astellas is announcing a Research Associate II, Process Science & Technology opportunity at their Astellas Institute of Regenerative Medicine (AIRM) site in Westborough, MA.


The Research Associate will execute studies required to develop new cell expansion processes, justify manufacturing process or product changes. These are to improve product performance and yield or identify critical parameters of processes in differentiated stem cell culture processes.

Essential Job Responsibilities:

  • Work closely with other Process Science and Technology (PST) team members, maintain accurate records and assist scientists with recording experimental data

  • Perform short- and long-term cell culture experiments

  • Maintain adherent mammalian cell cultures, including media preparation, thawing & seeding, feeding, passaging and cryopreservation of cells

  • Perform assays such as viability, cell growth and flow cytometry

  • Assist in planning and implementing the development of new processing materials, procedures and products

  • Assist in establishing process parameters and improving manufacturing efficiencies especially in the areas of differentiation, expansion and activation of Natural Killer cells

Quantitative Dimensions:

The work will focus on development of new clinical trial products and processes. Successful completion of tasks will lead to technology transfer into GMP manufacturing, improvements in production efficiencies and product safety.

Organizational Context:

This position reports to Senior Scientist in the PST group. The individual will work closely with other members of the PST staff and will interact with Drug Product Development, Analytical Development and Translational Development groups.



  • BS with 3+ years or MS with 0-2 years of laboratory experience.

  • Proficient in aseptic technique, mammalian cell culture and basic molecular biology techniques (DNA/RNA prep, qPCR, etc.).

  • Broad-based knowledge of cell biology.

  • Exceptional oral and written skills.


  • Experience with culture and differentiation of hematopoietic cells such as NK or T-cells.

  • Previous experience in process development of cell-based products.

  • Knowledge of or previous cGMP experience.


  • Medical, Dental and Vision Insurance

  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down

  • 401(k) match and annual company contribution

  • Company paid life insurance

  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

  • Long Term Incentive Plan for eligible positions

  • Referral bonus program


Category Research and Development

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans