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Astellas Pharma Research Associate II, Cell Based Therapies in Westborough, Massachusetts

Research Associate II, Cell Based Therapies

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at .

Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma Inc and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.

AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell-based therapy research programs. AIRM is headquartered in Massachusetts.

Astellas is announcing a Research Associate II, Cell Based Therapies opportunity at their Astellas Institute of Regenerative Medicine (AIRM) site in Westborough, MA.


We are seeking a highly motivated and energetic Research Associate to join the Research and Development team. This candidate will assist and troubleshoot exploratory research projects by performing mammalian cell culture, cell, and molecular biology, and maintain accurate records for potential clinical applications. This position is highly collaborative, with on-the-job training to support the driven candidate's development and success.

Essential Job Responsibilities:

  • Perform mammalian cell culture (stem cells or epithelial/endothelial cells) using aseptic techniques

  • Ability to follow established protocols and execute in vitro assays, including transwell culture systems, cell viability assays, flow cytometry, and cell imaging

  • Maintains detailed, accurate record-keeping, contributing to SOPs and technical reports

  • Ensures availability of experimental materials

  • Familiarity with in vivo models

  • Summarizes results and communicates independently to team members

Quantitative Dimensions:

  • Understands and effectively conducts in vitro and in vivo experimentation to meet business objectives

  • Contributes to scientific discussion

Organizational Context:

  • Reports to Sr Scientist, R&D

  • Communicates with other members of multidisciplinary teams.



  • BS with 3+ years, or MS with 0-2 years of relevant laboratory experience.

  • Solid cell culture experience using aseptic technique, e.g. seeding, passaging, maintaining cells in culture, and banking cells

  • Familiarity with cell-based functional assays

  • Comfortable with in vivo models

  • Scientific curiosity coupled with desire to learn new skills

  • Superb written and oral communication skills to foster collaboration

  • Proficiency in Excel or GraphPad Prism, Word, PowerPoint

  • Ability to work flexible schedule, including weekends

  • Must have lawful immigration status to work legally for US firms


  • Experience with human adult stem cell culture, mesenchymal stem cells and endothelial/epithelial cells.

  • Experience with in vitro barrier models, such as cell stress, cell polarization, extravasation, transepithelial/endothelial electrical resistance.

  • Experience with microscope imaging, ELISA and PCR.

  • Expertise on cell lineage characterization immunoassays using flow cytometry, immunofluorescence, cell isolation using FACS sorting and magnetic beads isolation, etc.

  • Hands-on in vivo model experience (handling or in-life data capture)


  • Medical, Dental and Vision Insurance

  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down

  • 401(k) match and annual company contribution

  • Company paid life insurance

  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

  • Long Term Incentive Plan for eligible positions

  • Referral bonus program


Category Research and Development

Astellas is committed to equality of opportunity in all aspects of employment.

EOE including Disability/Protected Veterans