We are seeking an Associate Director/Senior Scientist who will help to advance development of cell therapy products at AIRM. He/she will lead translational studies in 2-3 therapeutic programs aimed at understanding biological mechanisms of action of cell therapy products

Essential Job Responsibilities:

  • Leads studies that aid in understanding and characterizing treatment effects on the underlying pathobiology

  • Efficiently collaborates with research and clinical scientists and externally, consults on clinical trial endpoints and their translation from/to preclinical model systems, serves as in-house consultant on scientific and technical issues

  • Designs and conducts non-clinical studies analyzes data, draws conclusions, makes suggestions based on results of experiments; writes study plans and technical reports, reviews study reports from collaborators and CROs

  • Demonstrates high level of independence in developing and executing research plans from hypothesis to conclusions, expert knowledge of cell biology principles and technical proficiency in research method

  • Stays current with scientific literature to proactively identify new objectives and approaches

  • Uses professional concepts and company policies and procedures to solve a wide range of difficult problems in creative and practical ways

  • Demonstrates technical proficiency, scientific creativity, efficient collaboration with others, and independent thought

  • Communicates effectively with manager, internal and external stakeholders

  • Creates a positive work environment promoting teamwork, mutual respect, encouraging change, innovation, and accountability at all levels

  • Ensures data are of high quality and the projects are on time and within budget; maintains accurate records as notebook/batch record/electronic entries in compliance with the Company policy

  • May contribute to writing documents for regulatory submissions, scientific manuscripts, technical reports, SOPs, patent applications

  • Carries out work in compliance with Astellas Health and Safety policies

  • May manage one or more employees and take part in their annual goal writing and performance appraisal ensuring that employee development objectives are met


  • BS, MS or Ph.D. degree in cell/molecular biology, or related scientific discipline with relevant post-degree laboratory research experience of 12+ years for BS, 8+ years for MS, or 5+ years for Ph.D. in a biotechnology/pharmaceutical industry or academic research.

  • Strong background in and demonstrated track record of accomplishments in cell biology

  • Result orientation and ability to work in a high paced environment

  • Knowledge of applicable laboratory equipment including automation

  • Demonstrated ability to independently design research strategy and effectively implement experiments in a timely manner, to analyze data, draw conclusions, make scientific recommendations and troubleshoot

  • Excellent communication skills and demonstrated proficiency in writing technical and scientific reports, scientific manuscripts, preparing presentations

  • Proven ability to work both independently and collaboratively across a global matrixed organization

  • Demonstrated ability to quickly learn new skills

  • Ability to work flexible hours and weekends/holidays

  • Efficiency at managing multiple projects while working under tight timelines

  • Flexibility and willingness to tackle new challenges outside of their comfort zone

  • Result-oriented, self-starter, team player


  • Backgroundinregenerative medicine, immunology, ophthalmology; Experience with pluripotent cells and their differentiated derivatives is strogngly preferred

  • Expertise in biology of cell adhesion and extracellular matrix

  • Familiarity with preclinical drug development, GLP/GMP environment

  • Working knowledge of omics data analysis, Next Generation Sequencing.

  • Proficiency with fit-for-purpose assay development.

  • Experience utilizing omics, flow cytometry, Nanostring, scRNA sequencing, molecular and/or cellular techniques to monitor disease activity and response to therapy

  • Working knowledge of statistical analysis tools

  • Experience in preclinical biomarker discovery

  • Working knowledge of statistical analysis software

  • proficiency in one or more of new high throughput platforms

  • Familiarity with queries on large biological datasets

  • Experience with writing SOPs,technology transfer, and training others

  • Demonstrated ability to establish and execute external collaborations with both academic laboratories and CROs

  • Benefits:

  • Medical, Dental and Vision Insurance

  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down

  • 401(k) match and annual company contribution

  • Company paid life insurance

  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

  • Long Term Incentive Plan for eligible positions

  • Referral bonus program

Category CMC Technical Operations

Astellas is committed to equality of opportunity in all aspects of employment.

EOE including Disability/Protected Veterans