About Astellas Gene Therapies

Astellas Gene Therapies is an Astellas Center of Excellence developing genetic medicines for patients with rare, life-threatening diseases. Based on our innovative approach to developing genetic medicines, as well as our industry-leading internal manufacturing capability and expertise, we have become the Astellas Center of Excellence for their newly-created Genetic Regulation Focus Area. We are currently exploring three gene therapy modalities: gene replacement, exon skipping gene therapy, and vectorized RNA knockdown, with plans to expand our focus and geographic reach under Astellas. We are based in San Francisco, with manufacturing and laboratory facilities in South San Francisco and Sanford, North Carolina. For more information, please visit our website: www.astellasgenetherapies.com

About Astellas

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are promoting the Focus Area Approach that is designed to identify opportunities for the continuous creation of new drugs to address diseases with high unmet medical needs by focusing on Biology and Modality. Furthermore, we are also looking beyond our foundational Rx focus to create Rx+® healthcare solutions that combine our expertise and knowledge with cutting-edge technology in different fields of external partners. Through these efforts, Astellas stands on the forefront of healthcare change to turn innovative science into value for patients. For more information, please visit our website at https://www.astellas.com/en.

Our Values:

  • Be BOLD (Find a Way)

  • Care Deeply – for our patients, each other and our work

  • #GSD (Get Stuff Done)

What is the catalyst for you in your professional career? Are you ready to be a part of a bold, innovative company, to make a change and to make a difference? Listed below is a current opening for a smart, driven, experienced, and just plain nice individual who wants to join us and be a part of our journey.

The Role

The primary purpose of the Senior Research Associate in Bioanalytics is to analyze tissue samples taken from our nonclinical research studies dosed with gene therapy candidates. The Senior Research Associate will process tissues for critical endpoints, run analysis on the appropriate instrument, and analyze data outcomes. In addition, the Senior Research Associate will QC data, optimize protocols, and assist in new assay development.

Job Responsibilities:

  • Extract protein, DNA and/or RNA from necropsied animal tissue

  • Run ddPCR, qPCR, ELISA, Western Blot etc analysis on tissue extracts

  • Sample analysis assay optimization

  • SOP writing

  • Data recording and analysis

  • QC analysis

Required Qualifications:

  • BS degree with 5+ or MS with 2+ years of laboratory experience

  • Ability to perform tissue extraction manually and on automated platforms

  • Proficient in qPCR & ddPCR

  • Proficient in RNA handling/storage and cDNA synthesis

  • Experienced using sterile technique and molecular assay handling

  • Proficient in QuantStudio Design and Analysis Software, QuantaSoft Software, and ImageJ

  • Experienced in quality control assessment

  • Experience in assay development/optimization


  • Experience with Quality Assurance compliance and GLP-like procedures

  • Experience with SOP writing

  • Experience with Electronic Notebook Record Keeping

Working Conditions:

  • This is a hands-on laboratory-based position that requires onsite work


  • Medical, Dental and Vision Insurance

  • Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks

  • 401(k) match and annual company contribution

  • Company paid life insurance

  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

  • Long Term Incentive Plan for eligible positions

  • Referral bonus program


Category Gene Therapy Research & Technical Operations

Astellas is committed to equality of opportunity in all aspects of employment.

EOE including Disability/Protected Veterans