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Astellas Pharma Scientist II, In Vitro Gene Therapy in South San Francisco, California

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at .

Astellas is announcing a Scientist I-II, In vitro Gene Therapy Vector Biosciences opportunity. This position is based in South San Francisco California.

About Astellas Gene Therapies

Astellas Gene Therapies is an Astellas Center of Excellence developing genetic medicines for patients with rare, life-threatening diseases. Based on our innovative approach to developing genetic medicines and our industry-leading internal manufacturing capability and expertise, we have become the Astellas Center of Excellence for their newly-created Genetic Regulation Focus Area. We are currently exploring three gene therapy modalities: gene replacement, exon skipping gene therapy, and vectorized RNA knockdown, with plans to expand our focus and geographic reach under Astellas. We are based in San Francisco, with manufacturing and laboratory facilities in South San Francisco and Sanford, North Carolina. For more information, please visit our website:

Our Values:

  • Be BOLD (Find a Way)

  • Care Deeply -- for our patients, each other, and our work

  • #GSD (Get Stuff Done)

What is the catalyst for you in your professional career? Are you ready to be a part of a bold, innovative company, make a change, and make a difference? Listed below is a current opening for a bright, driven, experienced, and just plain lovely individual who wants to join us and be a part of our journey.


Astellas Gene Therapies (formerly Audentes Therapeutics) is seeking an innovative and talented scientist with expertise in cell biology or tissue engineering to form part of the Vector Biosciences team located in our South San Francisco R&D laboratories. The successful candidate will develop assays to support the testing of our AAV gene therapy candidates and implement novel cell-based tools to advance our in vitro platform. The scientist will work within the Vector Biosciences team to progress early discovery research at Astellas Gene Therapies and develop superior in vitro systems for AAV vector characterization. The selected candidate will collaborate with scientists from In vitro Assay Development, Vector Research Core, Bioinformatics, and Bioanalytical groups at Astellas Gene Therapies. Additional responsibilities include overseeing projects carried out by external collaborators.

About you


A Ph.D. in Cell Biology, Biochemistry, Molecular Biology Tissue Engineering, Biotechnology, or a related field is required. Qualified candidates will have first-author publications in disciplines such as virology, cell biology, molecular biology, biochemistry, tissue engineering, or transcriptomics.

The ideal candidate should have demonstrated expertise and working knowledge in one or more of the following areas: cell-based 3D systems, in vitro cellular reprogramming, tissue engineering, or stem cell biology. Critical thinking and familiarity with standard molecular biology techniques including western blotting, qPCR/ RT-PCR, immunofluorescence, and microscopy are essential. The candidate must have the ability to apply scientific principles to solve complex problems.

The candidate must be a good communicator with solid presentation skills and the ability to investigate and convey complex projects both verbally and in writing. Expectations for this position include a robust work ethic, being highly collaborative, initiating and completing investigative projects within the expected time frames, and emphasizing accuracy and high-quality work.

Models our Core Values: Be Bold: Find a Way, Care Deeply, Get Stuff Done -- is experienced as someone who exemplifies the culture we want to create; operates with transparency; is trusted.


  • Experience with models for ophthalmology, cardiovascular, and neuromuscular diseases preferred

  • Experience working with viruses, especially Adeno-Associated Virus (AAV)

  • 0-2+ years of postdoctoral experience preferred


  • Medical, Dental and Vision Insurance

  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down

  • 401(k) match and annual company contribution

  • Company paid life insurance

  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

  • Long Term Incentive Plan for eligible positions

  • Referral bonus program


Category Research and Development

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans