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Astellas Pharma Postdoctoral Fellow: Gene Therapy Research Innovation & Technology in South San Francisco, California

Why Work for Us

Are you ready to use your experience and expertise to make an impact on patients' lives? Astellas Gene Therapies is a biotechnology company developing new genetic medicines for rare, life-threatening diseases. We are working urgently to progress our medicines and need additional team members to help us do so. Because our mission is so important, our values are to: Be BOLD: Find a Way, Care Deeply, and Get Stuff Done. If you'd like to be a part of this important mission, please apply to join our team.

About Astellas Gene Therapies

Astellas Gene Therapies is developing genetic medicines for patients with rare, life-threatening diseases. Based on our innovative approach to developing genetic medicines, as well as our industry-leading internal manufacturing capability and expertise, we have become the Astellas Center of Excellence for the newly created Genetic Regulation Focus Area. We are currently exploring three gene therapy modalities: gene replacement, exon skipping gene therapy, and vectorized RNA knockdown, with plans to expand our focus and geographic reach under Astellas. We are based in San Francisco, with manufacturing and laboratory facilities in South San Francisco and Sanford, North Carolina. For more information, please visit our website: .

Our Values:

  • Be BOLD (Find a Way)

  • Care Deeply -- for our patients, each other and our work

  • #GSD (Get Stuff Done)

What is the catalyst for you in your professional career? Are you ready to be a part of a bold, innovative company, to make a change and to make a difference? Listed below is a current opening for a smart, driven, experienced, and just plain nice individual who wants to join us and be a part of our journey.

The Role

Astellas Gene Therapies (formerly Audentes Therapeutics) is seeking an innovative and talented Postdoctoral Fellow with expertise in cell biology or tissue engineering to form part of the Vector Biosciences team located in our South San Francisco R&D laboratories. The successful candidate will investigate the bottlenecks in our in vitro platform with the goal of improving testing of our AAV gene therapy vector candidates. Success of this project will enable better in vitro systems for AAV vector characterization to support early discovery research at Astellas Gene Therapies. The selected candidate is expected to collaborate with scientists from In vitro Assay Development, Vector Research Core, Bioinformatics and Bioanalytical groups at Astellas Gene Therapies. Additional responsibilities include, providing scientific results that support the generation of publication or patents.

About you

Must Have/Required

A PhD in Tissue Engineering, Biotechnology, Biochemistry, Molecular Biology, Cell Biology, or a related field is required. Qualified candidates are expected to have first author publications in disciplines such as virology, cell biology, molecular biology, biochemistry, tissue engineering, and transcriptomics.

The ideal candidate should have expertise and working knowledge in cell biology, mammalian cell culture, and biochemistry. Critical thinking and familiarity with standard molecular biology techniques, western blotting, qPCR/ RT-PCR, and microscopy essential. The candidate must have the ability to apply scientific principles to solve complex problems.

The candidate must be a good communicator with strong presentation skills and the ability to investigate and convey complex projects both verbally and in writing. Expectations for this position include very strong work ethics, being highly collaborative, initiation and completion of investigative project within the expected time frames, and with emphasis on accuracy and high-quality work.

Models our Core Values: Be Bold: Find a Way, Care Deeply, Get Stuff Done -- is experienced as someone who exemplifies the culture we want to create; operates with transparency; is trusted

May Have/Preferred

  • Experience with in vitro models for neuromuscular diseases preferred

  • 0-2+ years of postdoctoral experience preferred


Category Innovation & Technology

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans