Engineering I, Process Development (Upstream)
Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.
About Astellas Gene Therapies
Astellas Gene Therapies is an Astellas Center of Excellence developing genetic medicines for patients with rare, life-threatening diseases. Based on our innovative approach to developing genetic medicines, as well as our industry-leading internal manufacturing capability and expertise, we have become the Astellas Center of Excellence for their newly-created Genetic Regulation Focus Area. We are currently exploring three gene therapy modalities: gene replacement, exon skipping gene therapy, and vectorized RNA knockdown, with plans to expand our focus and geographic reach under Astellas. We are based in San Francisco, with manufacturing and laboratory facilities in South San Francisco and Sanford, North Carolina. For more information, please visit our website: www.astellasgenetherapies.com.
Job Responsibilities:
Execute experiments at various Process Development scales and unit operations, specifically shake flasks and bioreactors.
Support design of experiments and analysis of results using basic statistical methods.
Analyze samples using various instruments & techniques (eg cell counters, spent media analyzers, chemistry kits).
Capture study data in appropriate formats (including paper records, digital repositories), ensuring Good Documentation Practices are followed.
Document and share study findings in presentations and reports.
Prepare study buffers and reagents.
Ensure lab instruments are maintained in proper working state by performing routine maintenance and coordinating vendor repairs.
Adhere to Process Development SOP/DOP documents. May review procedures and author SOP/DOPs.
Required Qualifications:
Bachelor’s degree in relevant Science or Engineering discipline. 2+ years industry experience.
Master’s degree in relevant Science or Engineering discipline. 0+ years industry experience.
Prior industry experience in relevant area (eg cell culture and bioreactor systems)
Preferred
Experience in production of AAV products.
Knowledge of statistical methods for experimental design and data analysis.
Working Conditions
- Hands-on lab-based position that requires onsite work.
Salary:
- $86,300 - $115,000 (NOTE: Final salary could be more or less, based on experience)
Benefits:
Medical, Dental and Vision Insurance
Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks
401(k) match and annual company contribution
Company paid life insurance
Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
Long Term Incentive Plan for eligible positions
Referral bonus program
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability
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Category GT - Technical Development
Astellas is committed to equality of opportunity in all aspects of employment.
EOE including Disability/Protected Veterans