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Astellas Pharma Scientist II, Cell Editing in Seattle, Washington

Universal Cells is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells and have a major effort in R&D. We design and produce stem cells that avoid rejection, and we engineer cells with improved therapeutic properties, all through our world-class gene editing platform.

Our goal is to provide cells for regenerative medicine applications that can treat all patients. Through internal R&D and our corporate partnerships, we are pursuing a diverse range of disease indications, including blindness, cancer, vascular insufficiency, and autoimmune diseases.

Universal Cells is announcing a Scientist II, Production Cell Editing opportunity at their facility in Seattle, WA.


The primary purpose of the Production Cell Editing Scientist II is to provide scientific expertise towards AAV-mediated gene-editing of pluripotent stem cells to generate Universal Donor Cells. This position will oversee the Production Cell Editing team to ensure efficient operation and on-time delivery of pluripotent stem cells.

Universal Cells is a wholly-owned subsidiary of Astellas Pharma. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's health around the world through the provision of innovative and reliable pharmaceutical products.

Essential Job Responsibilities:

  • Designs and executes AAV-mediated gene-editing of pluripotent stem cells in a controlled manufacturing environment.
  • Performs data collection, analysis and interpretation for stem cell culture and gene-editing processes.
  • Leads group meetings and regularly presents at cross-functional team meetings.
  • Prepares and reviews the work of others to include, but not limited to, technical slide decks, reports, Standard Operating Procedures (SOPs) and production batch records.
  • Serves as a technical resource for preparation of regulatory filings.
  • Supports Process Development to establish and transfer manufacturing processes.
  • Supports Process Development to identify and troubleshoot challenges in manufacturing operations. Serves as a subject matter expert on experiment methods and production processes.
  • Ensures smooth day-to-day operations of manufacturing lab.
  • Performs other duties as assigned or special projects as needed



  • A Ph.D. in biology, genome sciences, or a related discipline with 3+ years of relevant post-graduate experience, or a MS with 7+ years, or a BS with 10+ years of highly relevant experience
  • Strong organizational, time management, and problem solving skills with scientific attention to detail
  • Ability to work independently and ability to effectively collaborate with other teams
  • Excellent communication and interpersonal skills
  • Excellent work planning, organization and record keeping
  • Strong work ethic with a passion for working in a fast-paced, dynamic and diverse work environment


  • Experience in leading teams highly preferred


Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled

Category Research and Development