Research Associate II, In Vivo

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.

Universal Cells , an affiliate of Astellas located in Seattle, WA, is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells to produce cells that avoid rejection and can be used in allogeneic cell therapy treatments to treat all patients that need them.

OUR GOAL - ONE CELL FOR EVERYONE

NO IMMUNE SUPPRESSION. NO DONOR MATCHING. NO REJECTION.

We are a dynamic team of research and scientific professionals who are passionate about turning science and innovation into medical solutions. Through our diversity, scientific knowledge, professional rigor and focus on innovation, we are merging our technology with the Astellas drug development expertise to unlock cures to many therapies. Join our team of committed, enthusiastic professionals devoted to making the most effective, life-saving cell therapy products in the world.

Universal Cells (UCI) is announcing a Research Associate II, In Vivo opportunity at their facility in Seattle, WA .

Purpose:

The primary purpose of the Research Associate II is to perform in vivo studies supporting the development of novel stem cell derived cellular therapies. This position will work primarily in a laboratory/vivaruim setting with Scientist and R&D teams.

Essential Job Responsibilities:

• Participates in developing, optimizing and troubleshooting in vivo models of oncology and autoimmunity in rodents

• Performs and interprets preclinical efficacy studies, including dosing, measurements, and post-procedural monitoring

• Collaborates with supervisory personnel to design, schedule, and execute in vivo experiments

• Assists in maintaining vivarium infrastructure

• Performs experiments with a careful attention to detail

• Accurately records procedures, data, and results

• Interprets data, draws conclusions from experimental work, and presents in team meetings

• Collaborates across teams within R&D, and other teams within Universal Cells

• Performs other duties as assigned or special projects as needed

Quantitative Dimensions:

• Direct impact on Universal Cells in vivo program for proof of concept translational studies.

Organizational Context:

• Reports to Department Leader

• Collaborates regularly with the Scientists and other R&D teams

• Interacts with external CROs

Qualifications:

Required:

• BS degree with 3+ years or MS with 0-2 years of laboratory experience

• Hands-on experience with in vivo models of oncology, immunology and autoimmunity, including proficiency in multiple routes of administration (IP, IV, SC, IM, etc.), organ and tissue harvesting, and blood collection techniques

• Ability to review, comprehend, and comply with all standard operating procedures (SOPs) and quality assurance standards pertaining to laboratory animals

• Diligence, and meticulous attention to detail in experimentation and record keeping

• Willingness to learn and enthusiasm to be part of the development of a cutting-edge therapy platform

• Ability to analyze and interpret data

• Strong organizational, time management, problem solving skills and the ability to work on several projects simultaneously

• Ability to work independently with supervision and ability to effectively collaborate across teams

• Excellent communication and interpersonal skills and genuine care for animals

Preferred:

• Strong scientific training and laboratory skills in stem cell biology, immunology, immuno-oncology, and oncology

• Hands-on experience with ex vivo tissue processing, including immune cell isolation and characterization by flow cytometry, multiplex immunohistochemistry, and other ex vivo assays

• Experience with in vivo imaging techniques

• Experience in cell culture and cell line maintenance

• AALAS certification a plus

Benefits:

• Medical, Dental and Vision Insurance

• Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down

• 401(k) match and annual company contribution

• Company paid life insurance

• Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

• Long Term Incentive Plan for eligible positions

• Referral bonus program

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Category Research and Development

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans