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Astellas Pharma Research Associate II, Immunology in Seattle, Washington

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.

Universal Cells , an affiliate of Astellas located in Seattle, WA, is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells to produce cells that avoid rejection and can be used in allogeneic cell therapy treatments to treat all patients that need them.

OUR GOAL - ONE CELL FOR EVERYONE

NO IMMUNE SUPPRESSION. NO DONOR MATCHING. NO REJECTION.

We are a dynamic team of research and scientific professionals who are passionate about turning science and innovation into medical solutions. Through our diversity, scientific knowledge, professional rigor and focus on innovation, we are merging our technology with the Astellas drug development expertise to unlock cures to many therapies. Join our team of committed, enthusiastic professionals devoted to making the most effective, life-saving cell therapy products in the world.

Universal Cells (UCI) is announcing a Research Associate II, Immunology opportunity at their facility in Seattle, WA .

Purpose:

The primary purpose of the Research Associate II is to conduct research focused on generating and characterizing cells derived from pluripotent stem cells. This position will work primarily in a laboratory setting with a lead Scientist and R&D teams.

Essential Job Responsibilities:

  • Participate in vivo work, including mouse model development and studies to characterize differentiated cells derived from pluripotent stem cells.

  • Culture and maintain human pluripotent stem cells and other primary immune cells.

  • Phenotype diverse cell types using a variety of assays, including multi-color flow cytometry.

  • Differentiate human pluripotent stem cells into various hematopoietic cell types, including work on differentiation protocol development and optimization towards critical parameters.

  • Perform experiments independently with careful attention to detail, accurately records procedures/data/results in a timely manner.

  • Interprets data, draws appropriate conclusions from experimental work, and presents findings in team meetings.

  • Closely collaborate with other members of the R&D team and other teams within Universal Cells to support multi-disciplinary studies.

  • Performs other duties as assigned or special projects as needed.

Quantitative Dimensions:

  • Direct impact on research related to pre-clinical research programs.

  • Potential to generate intellectual property.

  • Assay and protocol development.

Organizational Context:

  • Reports to Senior Scientist

  • Collaborates regularly with Scientists and RA's on other R&D teams

Qualifications:

Required:

  • BS degree with 3+ years or MS with 0-2 years of relevant laboratory experience.

  • Experience in mammalian cell culture, including primary immune cells.

  • Previous experience performing multiparameter flow cytometry and data analysis (FlowJo).

  • Demonstrated experience in assay and/or protocol development.

  • Familiarity with immune cell phenotyping and relevant functional assays (i.e. mixed leukocyte reactions (MLRs), ELISA/multiplex biomarker analysis).

  • Diligence and meticulous attention to detail in experimentation and record keeping.

  • Willingness to learn and enthusiasm to be part of the development of a cutting-edge therapy platform.

  • Strong organizational, time management, and problem-solving skills.

  • Ability to work independently with supervision and ability to effectively collaborate with other teams.

  • Excellent communication and interpersonal skills.

  • Ability to work weekends, as needed.

Preferred:

  • Hands-on experience with in vivo models, including proficiency in multiple routes of administration, organ and tissue harvesting, and blood collection techniques strongly preferred.

  • Prior work in human pluripotent stem cell culture and differentiation.

  • Experience with molecular biology (include DNA/RNA isolation, PCR, and gene expression analysis).

  • Relevant background in the fields of immunology, hematopoiesis, cancer, or autoimmunity.

Benefits:

  • Medical, Dental and Vision Insurance

  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down

  • 401(k) match and annual company contribution

  • Company paid life insurance

  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

  • Long Term Incentive Plan for eligible positions

  • Referral bonus program

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Category Research and Development

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans

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