Astellas Pharma Research Associate II, Cell Editing in Seattle, Washington
Universal Cells is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells and have a major effort in R&D. We design and produce stem cells that avoid rejection, and we engineer cells with improved therapeutic properties, all through our world-class gene editing platform.
Our goal is to provide cells for regenerative medicine applications that can treat all patients. Through internal R&D and our corporate partnerships, we are pursuing a diverse range of disease indications, including blindness, cancer, vascular insufficiency, and autoimmune diseases.
Universal Cells (UCI) is announcing a Research Associate II, Cell Editing opportunity at their facility in Seattle, WA.
The primary purpose of the Research Associate II for Cell Editing is to support the generation of clinical-grade, gene-edited Universal Donor Cells in a controlled manufacturing environment. The Cell Editing Research Associate II will work as part of a team evaluating, planning, and executing all aspects of gene-editing and engineering of pluripotent stem cells. This position follows routine procedures, utilizes solid technical knowledge, understands administrative operations, and general troubleshooting. Will assist with complex laboratory operations and generate content for various documents and reports. Will be able to execute protocols with minimal guidance and will have the ability to summarize results with supervisory guidance.
Universal Cells is a wholly-owned subsidiary of Astellas Pharma. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's health around the world through the provision of innovative and reliable pharmaceutical products.
Essential Job Responsibilities:
- Designs and executes AAV-mediated gene-editing of pluripotent stem cells in a controlled manufacturing environment.
- Performs data collection, analysis and interpretation for stem cell culture and gene-editing processes.
- Participates in group meetings and regularly presents at cross-functional team meetings.
- Prepares and reviews the work of others, including but not limited to, technical slide decks, reports, Standard Operating Procedures (SOPs) and production batch records.
- May serve as a technical resource for preparation of regulatory filings.
- Supports Process Development to transfer manufacturing processes.
- Supports Process Development to identify and troubleshoot challenges in manufacturing operations.
- Serves as a subject matter expert on experimental methods and production processes.
- Ensures smooth day-to-day operations of manufacturing lab.
- Performs other duties as assigned or special projects as needed.
- An MS with 0-2 years or a BS with 3+ years of highly relevant laboratory experience.
- Strong organizational, time management and problem-solving skills with scientific attention to details.
- Ability to work independently and ability to effectively collaborate with other teams.
- Excellent communication and interpersonal skills.
- Excellent work planning, organization, and record keeping.
- Strong work ethic with a passion for working in a fast-paced, dynamic and diverse work environment.
- Experience with pluripotent stem cell culturing.
- Experience with gene editing of pluripotent stem cells.
- Experience working in a GMP environment.
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled Category Research and Development