Astellas Pharma Research Associate I, Clinical Gene Editing in Seattle, Washington
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Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.
Universal Cells , an affiliate of Astellas located in Seattle, WA, is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells to produce cells that avoid rejection and can be used in allogeneic cell therapy treatments to treat all patients that need them.
OUR GOAL - ONE CELL FOR EVERYONE
NO IMMUNE SUPPRESSION. NO DONOR MATCHING. NO REJECTION.
We are a dynamic team of research and scientific professionals who are passionate about turning science and innovation into medical solutions. Through our diversity, scientific knowledge, professional rigor and focus on innovation, we are merging our technology with the Astellas drug development expertise to unlock cures to many therapies. Join our team of committed, enthusiastic professionals devoted to making the most effective, life-saving cell therapy products in the world.
Universal Cells (UCI) is announcing a Research Associate I, Clinical Gene Editing opportunity at their facility in Seattle, WA .
The primary purpose of the Research Associate I is to support the generation of clinical-grade, gene-edited Universal Donor Cells in a controlled manufacturing environment. This entry-level Research Associate role will work as part of a team planning and executing all aspects of gene-editing and engineering of pluripotent stem cells. This position will be provided training to perform all required fundamental skills to include record keeping, aseptic technique/cell culture, general lab operations, equipment use and maintenance, and some troubleshooting. Will assist with basic laboratory operations, and will keep appropriate documentation, including lab notebooks, batch documentation and experimental summaries. May assist in preparing controlled documents and data summaries.
Essential Job Responsibilities:
75% of the time will be spent in the laboratory environment on specified projects editing pluripotent stem cells using aseptic cell culture technique.
Assists with the designing and execution of AAV-mediated gene-editing of pluripotent stem cells in a controlled manufacturing environment.
Demonstrates understanding and ability to record data using Good Documentation Practices.
Demonstrates ability to write and follow established SOPs.
Assists with data collection, analysis and interpretation for stem cell culture and gene-editing processes.
Communicates results in both oral and written formats in a timely manner and actively participates in team meetings and presentation preparations.
Shows willingness to learn new protocols, relevant equipment, and related software.
May support Process Development to tech transfer in manufacturing processes.
May support Process Development to identify and troubleshoot challenges in manufacturing operations.
Ensures smooth day-to-day operations of the manufacturing lab.
Performs other duties as assigned or special projects as needed.
The Research Associate I will be trained to have complete competency in laboratory environment, with full team integration within 6 months. Once trained, they will move to support cell culture and data analysis activities for all cell editing projects.
The Research Associate I is an entry-level role for our Cell Editing team that ensures technical execution, documentation, and real-time communication of gene-editing production activities to facilitate advancement of clinical candidates.
This position reports to Director of Process Development and Cell Editing.
Operates on a shifted schedule that includes at least one weekend day.
BS Degree with 0-3 years of relevant hands-on laboratory experience.
Solid working knowledge of aseptic mammalian cell culture technique.
Strong working knowledge of clinical-grade manufacturing.
Strong organizational, time management skills, and the ability to maintain accurate and up-to-date records.
Ability to work effectively both independently and with other team members.
Excellent communication and interpersonal skills.
Strong work ethic with a passion to learn and work in a fast-paced, dynamic and diverse work environment.
Ability to troubleshoot and think critically, with scientific attention to detail.
Flexibility to work shifted schedule with at least one weekend day.
This role will be on a shifted schedule, either Tuesday to Saturday OR Sunday to Thursday.
Knowledge of Good Documentation Practices, Good Manufacturing Practices and working within Quality Systems
Experience with pluripotent stem cell culturing.
Experience with gene editing of pluripotent stem cells.
Experience working in a GMP environment.
Medical, Dental and Vision Insurance
Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
401(k) match and annual company contribution
Company paid life insurance
Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
Long Term Incentive Plan for eligible positions
Referral bonus program
Category Research and Development
Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans