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Astellas Pharma Research Associate I, Cell Editing in Seattle, Washington

Universal Cells is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells and have a major effort in R&D. We design and produce stem cells that avoid rejection, and we engineer cells with improved therapeutic properties, all through our world-class gene editing platform. Our goal is to provide cells for regenerative medicine applications that can treat all patients. Through internal R&D and our corporate partnerships, we are pursuing a diverse range of disease indications, including blindness, cancer, vascular insufficiency, and autoimmune diseases. Universal Cells (UCI) is announcing a Research Associate I, Cell Editing opportunity at their facility in Seattle, WA. Purpose: The primary purpose of the Research Associate I for Cell Editing is to support the generation of clinical-grade, gene-edited Universal Donor Cells in a controlled manufacturing environment. This entry-level Research Associate role will work as part of a team planning and executing all aspects of gene-editing and engineering of pluripotent stem cells. This position will be provided training to perform all required fundamental skills to include record keeping, aseptic technique/cell culture, general lab operations, equipment use and maintenance, and some troubleshooting. Will assist with basic laboratory operations, and will keep appropriate documentation, including lab notebooks, batch documentation and experimental summaries. May assist in preparing controlled documents and data summaries. Universal Cells is a wholly-owned subsidiary of Astellas Pharma. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's health around the world through the provision of innovative and reliable pharmaceutical products. Essential Job Responsibilities: * 75% of the time will be spent in the laboratory environment on specified projects editing pluripotent stem cells using aseptic cell culture technique. * Assists with the designing and execution of AAV-mediated gene-editing of pluripotent stem cells in a controlled manufacturing environment. * Demonstrates understanding and ability to record data using Good Documentation Practices. * Demonstrates ability to write and follow established SOPs. * Assists with data collection, analysis and interpretation for stem cell culture and gene-editing processes. * Communicates results in both oral and written formats in a timely manner and actively participates in team meetings and presentation preparations. * Shows willingness to learn new protocols, relevant equipment, and related software. * May support Process Development to tech transfer in manufacturing processes. * May support Process Development to identify and troubleshoot challenges in manufacturing operations. * Ensures smooth day-to-day operations of the manufacturing lab. * Performs other duties as assigned or special projects as needed. Qualifications: Required * BS Degree with 0-3 years of relevant hands-on laboratory experience. * Strong organizational, time management skills, and the ability to maintain accurate and up-to-date records. * Ability to work effectively both independently and with other team members. * Excellent communication and interpersonal skills. * Strong work ethic with a passion to learn and work in a fast-paced, dynamic and diverse work environment. * Ability to troubleshoot and think critically, with scientific attention to detail. * Flexibility to work shifted schedule with at least one weekend day. Preferred * Experience with aseptic mammalian cell culture technique. * Experience with pluripotent stem cell culturing. * Experience with gene editing of pluripotent stem cells. * Knowledge of Good Documentation Practices, Good Manufacturing Practices and working within Quality Systems #LI-JA1 Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled Category Research and Development