Astellas Pharmaceutical Jobs

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Astellas Pharma Senior Project Operations Manager in Northbrook, Illinois

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at

This position is based in Northbrook, Illinois. Remote work from certain states may be permitted in accordance with Astellas' Responsible Flexibility Guidelines. Candidates interested in remote work are encouraged to apply.

Purpose & Scope:

Business Operations Strategy -- a group within the Strategic Planning & Communications Department - facilitates transformational initiatives within and across Medical &Development (M&D) organizations to improve how Astellas delivers innovative medicines to patients. These improvement programs include internal initiatives ranging from organizational changes, process improvement, and IT platform implementation. BOS also ensures alignment of these cross functional initiatives with M&D's forward-looking business strategy.

The Senior Project Operations Manager will be responsible for supporting business case development, managing program delivery, drafting program deliverables and ensuring alignment with other initiatives impacting M&D. Facilitating teams to embed global transformational changes will require a strong grasp of business analytics, stakeholder management, project coordination and change management faculties.

Essential Job Responsibilities:

Key responsibilities include:

  • Responsible for developing, implementing and coordinating program deliverables for assigned internal improvement initiatives, which may include process improvement, organizational, or technical implementation.

  • Build business cases and project strategy documentation for proposed initiatives in partnership with program leadership, sponsors, and central operations teams

  • Support project/program leadership with facilitating workshops, performing options analyses and defining requirements.

  • Support project/program leadership to drive project, scope, schedule, resource, cost, risk, management plans

  • Support project/program leadership to drive building of delivery plan, critical path, translation into timeline, and alignment of resource assignments.

  • Support project/program leadership to identify/track dependencies/interdependencies impacting project delivery and adjust plans accordingly

  • Responsible to drive project/program execution according to established management plans

  • Manage conflict within any program in an effective, timely, and appropriate manner

  • Proactively track, manage, & escalate risks to leadership, including developing options for mitigation

  • Capture/Share best practices to enhance learning & improvement within the operations organizations

Quantitative Dimensions:

  • Responsible for evaluating program value and aligning with M&D priorities

  • Responsible for budget, resource, and timelines associated with assigned initiatives as well as periodic reporting to leadership

Organizational Context:

Position reports to the Director of BOS - Project and Portfolio Operations. Collaborates with transformational project leads, business owners, cross functional peers, subject matter experts, and functional leaders and all functions within M&D to drive initiatives forward and ensure deliverables are met.




  • BA/BS


  • Minimum 8 years in the pharmaceutical industry and/or management consulting group focused on R&D, clinical development or medical affairs.

  • Strong command of project management capabilities, including developing and managing timelines, budgets, and risks, as well as experience with matrixed leadership & facilitation and business case development.

  • Strong command of business analytics, including analyzing current state operations, building and defining recommendations, defining processes and requirements, as well as implementing those changes.

  • Demonstrated leadership skills in a matrix organization with a successful track record of accomplishing high quality results through team level performance.

  • A key organizer with demonstrated prioritization of developmental activities; finances with experience in financial reporting and planning systems/processes.

  • Knowledge of the Software Development Life Cycles and Computer System Validation expectations.

  • Knowledge of enterprise-wide pharmaceutical software solutions and application in industry; strong knowledge of assigned software solution.

  • Proven track record of facilitating process optimization and process change initiatives in a cross-functional setting.

  • Excellent oral and written communication and presentation skills, in English, with an ability to interact at all levels of personnel.

  • Experience working cross-functionally and cross-culturally in support of business processes and/or systems, especially as they impact and influence multiple departments and levels of management

  • Strong and effective strategic thinker and problem solver with high degree of emotional intelligence, with the ability to both recognize and anticipate problems.

  • Demonstrated ability to effectively build business relationships and influence without authority as part of a matrix organization.

  • May require up to 10% international travel.

  • Excellent understanding of the interdependencies of the various disciplines (CMC, Pharm/Tox, PK, Clinical, Regulatory, Marketing, Compliance, and Legal)

  • Excellent computer skills (MS Office Suite, including MS Visio and MS Project Plan)


  • Advanced degree, MBA, MS or equivalent

  • Project management certification, PMP/LSS or equivalent


  • Medical, Dental and Vision Insurance

  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down

  • 401(k) match and annual company contribution

  • Company paid life insurance

  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

  • Long Term Incentive Plan for eligible positions

  • Referral bonus program


Category Medical & Development

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans