Astellas Pharma Research Associate, Ocular/Neuroscience in Marlborough, Massachusetts
The Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.
Developing innovative therapies is one of the most challenging, most essential and personally rewarding fields in science. This is the most exciting time to be a part of Astellas, a company with a uniquely collaborative and patient-focused culture. There's something special about working at Astellas. It's reflected in our focus on the people we serve, the way we treat each other and the results we achieve together as a company.
AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell based therapy research programs. AIRM is headquartered in Marlborough, Massachusetts.
Purpose & Scope:
The Research Associate, Ocular/Neuroscience performs research and/or development of pluripotent stem cell (PSC)-derived ocular/neuronal cell products. The incumbent will play an important role in advancing pipeline products through meticulous individual contributions and collegial interactions/collaborations with other team members.
Essential Job Responsibilities:
- Generation of PSC-derived ocular/neuronal cell lines by careful execution of established differentiation protocols.
- In vitro characterization of PSC-derived ocular/neuronal cell lines through established molecular and cell biology techniques and functional assays.
- Participation in rodent transplantation studies, histological analyses, and/or functional in vivo/ex vivo assays.
- Makes recommendations for changes to experimental procedures to improve quality or productivity.
- Ensures availability of all experimental materials.
- Understands and carries out the proper use and maintenance of laboratory equipment.
- Maintenance of laboratory notebook and communication/presentation of results.
- Keeps current on relevant published literature and developments in the field.
- B.S./M.S. in molecular and cell biology, neurobiology, vision science or related field, plus 2 or more years of relevant experience.
- Must possess solid working knowledge of aseptic cell culture technique: growing, passaging, maintaining cells in culture.
- Experience with routine molecular and cell biology techniques, histological tissue processing, immunofluorescence staining, microscopy, and/or rodent handling.
- The ability to perform laboratory assays in an accurate and reproducible manner by following established protocols.
- Excellent written and oral communication skills.
- The ability to work well as a collaborative and collegial team member.
- Experience with pluripotent stem cell culture, stem cell differentiation, and/or neuronal cell culture.
The statements above are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time.
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled
Category Research and Developmemt