Astellas Pharma Research Associate I in Marlborough, Massachusetts
The Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.
Developing innovative therapies is one of the most challenging, most essential and personally rewarding fields in science. This is the most exciting time to be a part of Astellas, a company with a uniquely collaborative and patient-focused culture. There's something special about working at Astellas. It's reflected in our focus on the people we serve, the way we treat each other and the results we achieve together as a company.
AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell based therapy research programs. AIRM is headquartered in Marlborough, Massachusetts.
We are seeking a highly motivated Research Associate, who will work on multiple stem cell and exosome related projects at AIRM. The research associate will be supporting cell culture and differentiation needs for the ocular team. They will also provide technical support for cell characterization through qPCR, ICC etc. They will also be supporting the extracellular vesicle (EV) team for multiple projects for EV isolation, characterization, in vivo studies etc.
Essential Job Responsibilities:
- Responsible for culturing, maintenance, characterization and differentiation of pluripotent stem cell lines
- Perform RNA and Protein expression analysis using qPCR, ICC/IHC, ELISA, FACS, and Western Blotting
- Make detailed observations, analyze data, interpret results, data visualization, and maintain records
- Participate in team discussions and contribute to experimental design
- Ensure proper maintenance of laboratory equipment
- Establish strong collaboration and communication across multiple research teams
- Bachelor's Degree with 0-3 years of experience; OR, Biotechnology Certification or Associates Degree with 2-4 years of experience
- Experience in techniques such as: immunocytochemistry/immunohistochemistry, western blotting, and flow cytometry, DNA/RNA prep, qPCR, and ELISA
- Basic sterile mammalian cell culture and cell handling
- Well organized, detail-oriented, adhere to SOPs, data collection, data management, and record keeping
- Excellent oral and written communication, and interpersonal skills
- Ability to work both independently and in a team setting, willingness to learn new skills
- Adept learner with an ability to identify and troubleshoot complex problems
- Experience in stem cell research including cell culture, cell characterization, and differentiation
- Experience in the ocular field is preferred
- Experience in extracellular field including exosomes isolation and characterization is a plus
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled
Category Research and Development